Genipin

Product Name: Genipin
CAS No.: 6902-77-8
Chemical Name: Genipin
Synonyms: enipin;GENIPIN;Jingping;Genipin>GENIPIN(SH);GENIPIN(RG);(+)-Genipin;Genipin, >=98%;Gardenia Fruit P.E;Genipin, food grade
CBNumber: CB9767199
Molecular Formula: C11H14O5
Formula Weight: 226.23
MOL File: 6902-77-8.mol

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Genipin Property

Melting point:: 118.0 to 123.0 °C
Boiling point:: 287.83°C (rough estimate)
Density: 1.1230 (rough estimate)
refractive index: 1.4720 (estimate)
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO: ≥25mg/mL
form: powder
pka: 12.06±0.60(Predicted)
color: White to Almost white
λmax: 240nm(MeOH)(lit.)
InChI: InChI=1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2,5,7,9,11-12,14H,3-4H2,1H3/t7-,9-,11-/m1/s1
InChIKey: AZKVWQKMDGGDSV-BCMRRPTOSA-N
SMILES: [C@@H]1(O)OC=C(C(OC)=O)[C@@]2([H])CC=C(CO)[C@@]12[H]
CAS DataBase Reference: 6902-77-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 3/14-36/37/39
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: GY5828000
HazardClass: 6.1
PackingGroup: III
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G4796
Product name: Genipin
Purity: ≥98% (HPLC), powder
Packaging: 25mg
Price: $134
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHL80458
Product name: Genipin
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $465
Updated: 2024/03/01

Sigma-Aldrich

Product number: G4796
Product name: Genipin
Purity: ≥98% (HPLC), powder
Packaging: 125mg
Price: $532
Updated: 2024/03/01

TCI Chemical

Product number: G0458
Product name: Genipin
Purity: >97.0%(GC)
Packaging: 25mg
Price: $57
Updated: 2024/03/01

TCI Chemical

Product number: G0458
Product name: Genipin
Purity: >97.0%(GC)
Packaging: 100mg
Price: $174
Updated: 2024/03/01

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Genipin Chemical Properties,Usage,Production

Chemical Properties

It is a white crystalline powder that is soluble in organic solvents such as methanol, ethanol, and DMSO. It is derived from the fruit of Gardenia jasminoides Ellis.

Uses

Genipin is an active aglycone derived from geniposide, an iridoid glycoside found in the fruit of Gardenia jasminoides Ellis. It has been used in traditional Chinese medicine and is a hydrolytic product of geniposide. Genipin is also known for its inhibitory effect on uncoupling protein 2 (UCP2).

Uses

Genipin has been used:

in chemosensitivity assay
in the preparation of recombinant human (rh)-odontogenic ameloblast-associated protein (ODAM) -impregnated collagen gel and in vitro mineralization assay
in genipin gel preparation

Definition

ChEBI: Genipin is an iridoid monoterpenoid. It has a role as an uncoupling protein inhibitor, a hepatotoxic agent, an apoptosis inhibitor, an antioxidant, an anti-inflammatory agent and a cross-linking reagent.

General Description

Genipin is a natural cross linking agent, which is extracted from gardenia fruit. It prevents lipid peroxidation and production of nitric oxide. Genipin protects the hippocampal neurons from the toxicity of Alzheimer′s amyloid β protein. It has anti-inflammatory and anti-angiogenesis effects. Genipin is involved in drug delivery system.

Biochem/physiol Actions

Genipin stimulates insulin secretion in UCP2-dependent manner (Uncoupling protein 2). Genipin is a protein, collagen, gelatin, and chitosan cross-linker.

Genipin Preparation Products And Raw materials

Raw materials

Preparation Products

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Genipin Suppliers

Americas 1 Canada 1 China 333 Czech Republic 1 Europe 1 Germany 4 India 5 Japan 2 Poland 1 Switzerland 1 The Netherlands 2 United Kingdom 7 United States 26 Global 385

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View Lastest Price from Genipin manufacturers

Hebei Shengyang Water Conservancy Engineering Co., Ltd.

Product: Genipin 6902-77-8
Price: US $18.00-18.00/kg
Min. Order: 1kg
Purity: 99.9
Supply Ability: 5000
Release date: 2024-05-10

Chongqing Zhihe Biopharmaceutical Co., Ltd.

Product: Genipin 6902-77-8
Price: US $0.00-0.00/kg
Min. Order: 0.10000000149011612kg
Purity: ≥98%
Supply Ability: 20tons
Release date: 2024-01-03

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Genipin 6902-77-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-04-29

6902-77-8, GenipinRelated Search:

Catalpol Cabazitaxel ASTRAGALIN Paclitaxel Icaritin Anhydroicaritin Docetaxel L-Epicatechin Nodakenin PINOCEMBRIN Geniposidic acid 1-β-Glucogeniposide Geniposide Genipin Geniposide std. Genipinic acid Genipic acid (1S,4AS,7AS)-7-HYDROXYMETHYL-1-((3R,4S,5S,6R)-3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLOXY)-1,4A,5,7A-TETRAHYDRO-CYCLOPENTA[C]PYRAN-4-CARBOXYLIC ACID METHYL ESTER

Methyl (1R,2R,6S)-2-hydroxy-9-(hydroxymethyl)-3-oxabicyclo[4.3.0]nona-4,8-diene-5-carboxylate

cyclopenta(c)pyran-4-carboxylicacid,1,4a-alpha,5,7a-alpha-tetrahydro-1-hydrox

GENIPIN

1,4a,5,7a-tetrahydro-1-hydroxy-7-(hydroxymethyl)-cyclopenta(c)pyran-4-carboxylic acid methyl ester

Methyl (1S,2R,6S)-2-hydroxy-9-(hydroxymethyl)-3-oxabicyclo[4.3.0]nona-4,8-diene-5-carboxylate

(1R)-1,4aα,5,7aα-Tetrahydro-1-hydroxy-7-hydroxymethylcyclopenta[c]pyran-4-carboxylic acid methyl ester

(1R)-1,4aα,5,7aα-Tetrahydro-1α-hydroxy-7-hydroxymethylcyclopenta[c]pyran-4-carboxylic acid methyl ester

enipin

Methyl (1S,2R,6S)-2-hydroxy-9-(hydroxymethyl)-3-oxabicyclo[4.3.0]nona-

GENIPIN(RG)

GENIPIN(SH)

Genipin, food grade

Cyclopenta[c]pyran-4-carboxylicacid, 1,4a,5,7a-tetrahydro-1-hydroxy-7-(hydroxyMethyl)-, Methyl ester,(1R,4aS,7aS)-

Genipin, >=98% (HPLC), powder

(1R,4aS,7aS)-methyl 1-hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate

7-Ethyl-1-hydroxy-1,4a,5,7a-tetrahydro-cyclopenta[c]pyran-4-carboxylic acid Methyl ester

Genipin, >=98%

Genipin&gt

Methyl (1R,4aS,7aS)-1-hydroxy-7- (hydroxymethyl)-1,4a,5,7a- tetrahydrocyclopenta[c]pyran-4- carboxylate

(+)-Genipin

GenipinQ: What is Genipin Q: What is the CAS Number of Genipin Q: What is the storage condition of Genipin Q: What are the applications of Genipin

Jingping

Gardenia Fruit P.E

6902-77-8

Inhibitors

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract